Recombinant Human RUFY3 Protein, MYC/DDK-tagged

• Cat.No.: RUFY3-2018H
• Product Overview: Recombinant human RUFY3 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 52.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: RUFY3 RUN and FYVE domain containing 3 [ Homo sapiens ]
• Official Symbol: RUFY3
• Synonyms: RIPX; SINGAR1; ZFYVE30
• Gene ID: 22902
• mRNA Refseq: NM_001037442
• Protein Refseq: NP_001032519
• MIM: 611194
• UniProt ID: Q7L099