Recombinant Human retinoic acid receptor responder (tazarotene induced) 1, His-tagged

• Cat.No.: RARRES1-203H
• Product Overview: RARRES1, 43-294aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 43-294 a.a.
• Description: Retinoic acid receptor responder protein 1 isoform 1, also known as RARRES1, belongs to the TIGs (Tazarotene-induced gene) family. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. Recombinant human RARRES1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
• Molecular Mass: 31.3kDa (275aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSPDDPGQP QDAGVPRRLL QQAARAALHF FNFRSGSPSA LRVLAEVQEG RAWINPKEGC KVHVVFSTER YNPESLLQEG EGRLGKCSAR VFFKNQKPRP TINVTCTRLI EKKKRQQEDY LLYKQMKQLK NPLEIVSIPD NHGHIDPSLR LIWDLAFLGS SYVMWEMTTQ VSHYYLAQLT SVRQWKTNDD TIDFDYTVLL HELSTQEIIP CRIHLVWYPG KPLKVKYHCQ ELQTPEEASG TEEGSAVVPT ELSNF
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: RARRES1 retinoic acid receptor responder (tazarotene induced) 1 [ Homo sapiens ]
• Official Symbol: RARRES1
• Synonyms: RARRES1; retinoic acid receptor responder (tazarotene induced) 1; retinoic acid receptor responder protein 1; TIG1; RAR-responsive protein TIG1; tazarotene-induced gene 1 protein
• Gene ID: 5918
• mRNA Refseq: NM_002888
• Protein Refseq: NP_002879
• MIM: 605090
• UniProt ID: P49788
• Chromosome Location: 3q25.32