Recombinant Human RBBP4 Protein, MYC/DDK-tagged

• Cat.No.: RBBP4-661H
• Product Overview: Recombinant human RBBP4 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 47.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: RB binding protein 4, chromatin remodeling factor[ Homo sapiens ]
• Official Symbol: RBBP4
• Synonyms: lin-53; NURF55; RBAP48
• Gene ID: 5928
• mRNA Refseq: NM_001135255.1
• Protein Refseq: NP_005601
• MIM: 602923
• UniProt ID: Q09028