Recombinant Human RASGRP2 protein, MYC/DDK-tagged
Cat.No. : | RASGRP2-33H |
Product Overview : | Recombinant Human RASGRP2, transcript variant 2, fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
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Species : | Human |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene. |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 69.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name | RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) [ Homo sapiens ] |
Official Symbol | RASGRP2 |
Synonyms | RASGRP2; RAS guanyl releasing protein 2 (calcium and DAG-regulated); RAS guanyl-releasing protein 2; CALDAG GEFI; hCDC25L; cdc25-like protein; F25B3.3 kinase-like protein; guanine exchange factor MCG7; RAS guanyl nucleotide-releasing protein 2; calcium and DAG-regulated guanine nucleotide exchange factor I; calcium and diacylglycerol-regulated guanine nucleotide exchange factor I; CDC25L; CALDAG-GEFI; |
Gene ID | 10235 |
mRNA Refseq | NM_153819 |
Protein Refseq | NP_722541 |
MIM | 605577 |
UniProt ID | Q7LDG7 |
Chromosome Location | 11q13 |
Pathway | Adaptive Immune System, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Effects of PIP2 hydrolysis, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Hemostasis, organism-specific biosystem; |
Function | calcium ion binding; calcium ion binding; diacylglycerol binding; guanyl-nucleotide exchange factor activity; lipid binding; |
◆ Recombinant Proteins | ||
RASGRP2-7438M | Recombinant Mouse RASGRP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
RASGRP2-913H | Recombinant Human RASGRP2 Protein, Myc/DDK-tagged, C13 and N15-labeled | +Inquiry |
RASGRP2-33H | Recombinant Human RASGRP2 protein, MYC/DDK-tagged | +Inquiry |
Rasgrp2-5390M | Recombinant Mouse Rasgrp2 Protein, Myc/DDK-tagged | +Inquiry |
RASGRP2-3610R | Recombinant Rhesus Macaque RASGRP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
RASGRP2-2505HCL | Recombinant Human RASGRP2 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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