Recombinant Mouse Rasgrp2 Protein, Myc/DDK-tagged

Cat.No. : Rasgrp2-5390M
Product Overview : Purified recombinant protein of mouse full-length RAS, guanyl releasing protein 2 (Rasgrp2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Species : Mouse
Source : HEK293
Tag : DDK&Myc
Description : Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway.
Molecular Mass : 69.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name Rasgrp2 RAS, guanyl releasing protein 2 [ Mus musculus (house mouse) ]
Official Symbol Rasgrp2
Synonyms RASGRP2; RAS, guanyl releasing protein 2; RAS guanyl-releasing protein 2; CalDAG-GEFI; F25B3.3 kinase like protein; F25B3.3 kinase-like protein; RAP 1A protein-specific guanine nucleotide exchange factor 1; calcium and DAG-regulated guanine nucleotide exchange factor I; CDC25L; Caldaggef1
Gene ID 19395
mRNA Refseq NM_011242
Protein Refseq NP_035372
UniProt ID Q9QUG9

Not For Human Consumption!

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