Recombinant Human RARS

• Cat.No.: RARS-26535TH
• Product Overview: Recombinant full length Human Arginyl tRNA synthetase with N-terminal proprietary tag. Predicted MW 98.71kDa.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: Non
• Protein Length: 660 amino acids
• Description: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Arginyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.
• Molecular Weight: 98.710kDa inclusive of tags
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MDVLVSECSARLLQQEEEIKSLTAEIDRLKNCGCLGASPN LEQLQEENLKLKYRLNILRKSLQAERNKPTKNMINIISRL QEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMG ISQMLKTKEQKVNPREIAENITKHLPDNECIEKVEIAGPG FINVHLRKDFVSEQLTSLLVNGVQLPALGENKKVIVDFSS PNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGD WGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRF DTEEEFKKRAYQCVVLLQGKNPDITKAWKLICDVSRQELN KIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDG RKIVFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEK ADMIIYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAG FGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEK ERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSF DKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLQKAAR ETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDY IYELATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEA VAAVMAKGFDILGIKPVQRM
• Sequence Similarities: Belongs to the class-I aminoacyl-tRNA synthetase family.

Gene Information

• Gene Name: RARS arginyl-tRNA synthetase [ Homo sapiens ]
• Official Symbol: RARS
• Synonyms: RARS; arginyl-tRNA synthetase; arginyl-tRNA synthetase, cytoplasmic; arginine tRNA ligase 1; cytoplasmic; DALRD1
• Gene ID: 5917
• mRNA Refseq: NM_002887
• Protein Refseq: NP_002878
• MIM: 107820
• Uniprot ID: P54136
• Chromosome Location: 5q35.1
• Pathway: Aminoacyl-tRNA biosynthesis, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, conserved biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, conserved biosystem; Cytosolic tRNA aminoacylation, organism-specific biosystem
• Function: ATP binding; arginine binding; arginine-tRNA ligase activity; ligase activity; nucleotide binding