Recombinant Human RAPSN Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RAPSN-4313H
• Product Overview: RAPSN MS Standard C13 and N15-labeled recombinant protein (NP_005046) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Molecular Mass: 46.1 kDa
• AA Sequence: MGQDQTKKQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKCWVARKALDKALDAIERAQDLAEEVGNKLSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEETELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFVTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RAPSN receptor-associated protein of the synapse [ Homo sapiens (human) ]
• Official Symbol: RAPSN
• Synonyms: RAPSN; receptor-associated protein of the synapse; receptor associated protein of the synapse, 43kD; 43 kDa receptor-associated protein of the synapse; CMS1D; CMS1E; rapsyn; RNF205; RING finger protein 205; 43 kda postsynaptic protein; acetylcholine receptor-associated 43 kda protein; RAPSYN; MGC3597
• Gene ID: 5913
• mRNA Refseq: NM_005055
• Protein Refseq: NP_005046
• MIM: 601592
• UniProt ID: Q13702