Recombinant Human Rap Guanine Nucleotide Exchange Factor (GEF) 4

• Cat.No.: RAPGEF4-2637H
• Product Overview: Recombinant human Rap Guanine Nucleotide Exchange Factor (GEF) 4 is expressed inE. coli.

Specification

• Cat. No.: RAPGEF4-2637H
• Description: Rap guanine nucleotide exchange factor (GEF) 4 (RAPGEF4), also known as exchange protein directly activated by cAMP 2 (EPAC2), is a protein which in humans is encoded by the RAPGEF4 gene.
• Source: E.coli.
• Form: Liquid.
• Formulation: In 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3.
• Biological Activity: EC50 of cAMP binding: ≤1.5 μM.
• Storage: +2°C to +8°C. Ship: Dry Ice Only.
• Tag: Non

Gene Information

• Gene Name: RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 [ Homo sapiens ]
• Synonyms:
  RAPGEF4; Rap guanine nucleotide exchange factor (GEF) 4; EPAC 2; OTTHUMP00000205058; RAP guanine-nucleotide-exchange factor (GEF) 4; cAMP-regulated guanine nucleotide exchange factor II; exchange factor directly activated by cAMP 2; exchange protein directly activated by cAMP 2; putative protein product of Nbla00496; rap guanine nucleotide exchange factor 4; CGEF2; EPAC2; Nbla00496; CAMP-GEFII
• Gene ID: 11069
• mRNA Refseq: NM_001100397
• Protein Refseq: NP_001093867
• MIM: 606058
• UniProt ID: Q8WZA2
• Chromosome Location: 2q31-q32
• Pathway: Leukocyte transendothelial migration; Diabetes pathways; Integration of energy metabolism; Integrin cell surface interactions
• Function: Ras GTPase binding; Ras guanyl-nucleotide exchange factor activity; cAMP binding; cAMP-dependent protein kinase regulator activity; guanyl-nucleotide exchange factor activity; nucleotide binding; protein binding