Recombinant Human RAB21, His-tagged

• Cat.No.: RAB21-3473H
• Product Overview: Recombinant human RAB21 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Ras-related protein Rab-21, also known as RAB21, is a member of the Ras superfamily of small GTP-binding proteins. Rab21 is integrin-associated protein and positive regulators of integrin traffic. This protein associate with the cytoplasmic domains of alpha-integrin chains and their expression influences the endo/exocytic traffic of integrins. This function of Rab21 is dependent on its GTP/GDP cycle and proper membrane targeting.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 200mM NaCl, 1mM PMSF
• Molecular Weight: 27.1kDa (242aa), confirmed by MALDI-TOF
• Purity: > 90% by SDS - PAGE
• Concentration: 0.5mg/ml (determined by Bradford assay)
• Sequences of amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMYSF KVVLLGEGCV GKTSLVLRYC ENKFNDKHIT TLQASFLTKK LNIGGKRVNL AIWDTAGQER FHALGPIYYR DSNGAILVYD ITDEDSFQKV KNWVKELRKM LGNEICLCIV GNKIDLEKER HVSIQEAESY AESVGAKHYH TSAKQNKGIE ELFLDLCKRM IETAQVDERA KGNGSSQPGT ARRGVQIIDD EPQAQTSGGG CC
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: RAB21 RAB21, member RAS oncogene family [ Homo sapiens ]
• Synonyms: ras-related protein Rab-21; RAB21; RAB21, member RAS oncogene family; KIAA0118; RAB21
• Gene ID: 23011
• mRNA Refseq: NM_014999
• Protein Refseq: NP_055814
• MIM: 612398
• UniProt ID: Q9UL25
• Chromosome Location: 12q21.1
• Function: GDP binding; GTP binding; GTPase activity; nucleotide binding; protein binding