Recombinant Human PTK2B Protein Tyrosine Kinase 2 Beta, GST-tagged

Cat. No. :	PTK2B-1903H
Description :	PTK2B is a cytoplasmic tyrosine kinaseinvolved in calcium-induced regulation of ion channels and activation of themap kinase signaling pathway. No special measures were taken to activate thiskinase.
Source :	Insect cells
Species :	Human
Form :	Liquid in 50 mMTris, pH 7.85 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT +50% glycerol.
Molecular Weight :	145.1 kDa
Storage :	Stablefor 6 months in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol :	PTK2B
Full Length :	Full L.

Gene Name	PTK2B PTK2B protein tyrosinekinase 2 beta [ Homo sapiens ]
Synonyms	PTK2B; PTK2B protein tyrosinekinase 2 beta; PTK2B protein tyrosine kinase 2 beta; CAK beta;calcium-dependent tyrosine kinase; cell adhesion kinase beta; focal adhesionkinase 2; proline-rich tyrosine kinase 2; protein kinase B; protein tyrosinekinase 2 beta; related adhesion focal tyrosine kinase; EC 2.7.10.2
Gene ID	2185
mRNA Refseq	NM_004103
Protein Refseq	NP_004094
MIM	601212
UniProt ID	Q14289
Chromosome Location	8p21.1
Pathway	Calcium signaling pathway;Chemokine signaling pathway; GnRH signaling pathway; Leukocytetransendothelial migration; Natural killer cell mediated cytotoxicity
Function	3-phosphoinositide-dependentprotein kinase binding; ATP binding; non-membrane spanning protein tyrosinekinase activity; nucleotide binding; protein complex binding; signaltransducer activity; transferase activity