Recombinant Human PRX Protein, MYC/DDK-tagged

• Cat.No.: PRX-3064H
• Product Overview: Recombinant Human PRX protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 15.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PRX periaxin [ Homo sapiens ]
• Official Symbol: PRX
• Synonyms: CMT4F; CMT4F
• Gene ID: 57716
• mRNA Refseq: NM_020956
• Protein Refseq: NP_066007
• MIM: 605725
• UniProt ID: Q9BXM0