Recombinant Human Protein Kinase D1, GST-tagged, Active

• Cat.No.: PRKD1-406H
• Product Overview: Recombinant human full-length PKCmu was expressed by baculovirus inSf9 cellsusing an N-terminal GST tag. MW=131 kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Description: Protein kinase Cmu (PKCμ) is a member of the protein kinase C (PKC) family that differs from the other PKC isoenzymes in structural and enzymatic properties. PKCμ is a ubiquitous in nature with the highest expression in the thymus, lung and peripheral blood mononuclear cells. PKCμ forms a complex in vivo with a phosphatidylinositol 4-kinase and a phosphatidylinositol-4-phosphate 5-kinase. A region of PKCμ between the amino-terminal transmembrane domain and the pleckstrin homology domain is shown to be involved in the association with the lipid kinases.
• Sequence: Full-length.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: PRKD1 protein kinase D1 [ Homo sapiens ]
• Synonyms: PRKD1; protein kinase D1; PKD; PKCM; PRKCM; PKC-MU; protein kinase C, mu; PKC-mu; Serine/threonine-protein kinase D1; EC 2.7.11.13; nPKC-D1; Protein kinase D; nPKC-mu; Protein kinase C mu type
• Gene ID: 5587
• mRNA Refseq: NM_002742
• Protein Refseq: NP_002733
• UniProt ID: Q15139
• Chromosome Location: 14q11
• MIM: 605435
• Pathway: Metabolism of lipids and lipoproteins
• Function: ATP binding; protein kinase C activity; nucleotide binding; transferase activity; zinc ion binding; magnesium ion binding; protein binding