Recombinant Human Protein Arginine Methyltransferase 6

• Cat.No.: PRMT6-453H
• Product Overview: Recombinant Human PRMT6, amino-acids 2-375(end), with N-terminal His-tag, MW=43 kDa, expressed in E. coli.

Specification

• Cat. No.: PRMT6-453H
• Description: Protein arginine N-methyltransferase 6 is an enzyme that in humans is encoded by the PRMT6 gene. Protein arginine N-methyltransferases, such as PRMT6, catalyze the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine.
• Source: E.coli
• Purity: >45%.
• Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Formulated In: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 200 mM imidazole, 20% glycerol, and 3 mM DTT.
• Stability: >6 months at –80°C.
• Tag: Non
• Protein length: 2-375 a.a.

Gene Information

• Gene Name: PRMT6 protein arginine methyltransferase 6 [ Homo sapiens ]
• Synonyms: PRMT6; protein arginine methyltransferase 6; HRMT1L6; FLJ10559; FLJ51477;EC 2.1.1.125; protein arginine N-methyltransferase 6; Histone-arginine methyltransferase PRMT6;EC2.1.1.-; Protein arginine N-methyltransferase 6; HMT1 hnRNP methyltransferase-like 6 (S. cerevisiae); Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6
• Gene ID: 55170
• mRNA Refseq: NM_018137
• Protein Refseq: NP_060607
• MIM: 608274
• UniProt ID: Q96LA8
• Chromosome Location: 1p13.2
• Function: histone binding; transferase activity; protein methyltransferase activity; histone methyltransferase activity (H2A-R3 specific); histone methyltransferase activity (H3-R2 specific); histone methyltransferase activity (H4-R3 specific); protein methyltransferase activity; protein-arginine omega-N asymmetric methyltransferase activity