Recombinant Human PRMT5/MEP50 complex Protein, Flag/His-tagged

• Cat.No.: PRMT5-178H
• Product Overview: Human recombinant PRMT5 in complex with human recombinant MEP50, produced by co-expression in an insect cell/baculovirus expression system with N-terminal Flag (PRMT5), N-terminal His (MEP50).

Specification

• Source: Insect cell
• Species: Human
• Tag: His&Flag
• Form: 50 mM Tris/HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM TCEP, 20% (v/v) glycerol.
• Molecular Mass: 73.7/39.90 kDa
• Protein length: PRMT5 2-637(C-term.), MEP50 2-342 (C-term.)
• Purity: >95% by SDS-PAGE
• Storage: Store at -80centigrade. Thaw quickly and store on ice before use. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: PRMT5 protein arginine methyltransferase 5 [ Homo sapiens ]
• Official Symbol: PRMT5
• Synonyms: PRMT5; protein arginine methyltransferase 5; HRMT1L5, SKB1, skb1 (S. pombe) homolog , SKB1 homolog (S. pombe); protein arginine N-methyltransferase 5; SKB1Hs; SKB1 homolog; jak-binding protein 1; 72 kDa ICln-binding protein; HMT1 hnRNP methyltransferase
• Gene ID: 10419
• mRNA Refseq: NM_001039619
• Protein Refseq: NP_001034708
• MIM: 604045
• UniProt ID: O14744
• Chromosome Location: 14q11.2
• Pathway: E2F transcription factor network, organism-specific biosystem; Gene Expression, organism-specific biosystem; Metabolism of non-coding RNA, organism-specific biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; Signali
• Function: histone-arginine N-methyltransferase activity; methyltransferase activity; protein binding; protein-arginine omega-N symmetric methyltransferase activity; ribonucleoprotein complex binding; transferase activity