Recombinant Human PRKRA Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PRKRA-654H
• Product Overview: PRKRA MS Standard C13 and N15-labeled recombinant protein (NP_003681) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 34.4 kDa
• AA Sequence: MSQSRHRAEAPPLEREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTDYIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERKTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PRKRA protein activator of interferon induced protein kinase EIF2AK2 [ Homo sapiens (human) ]
• Official Symbol: PRKRA
• Synonyms: PRKRA; protein kinase, interferon-inducible double stranded RNA dependent activator; interferon-inducible double stranded RNA-dependent protein kinase activator A; DYT16; HSD14; PACT; protein activator of the interferon induced protein kinase; RAX; PKR-associated protein X; PKR-associating protein X; protein activator of the interferon-induced protein kinase; protein kinase, interferon-inducible double stranded RNA-dependent activator
• Gene ID: 8575
• mRNA Refseq: NM_003690
• Protein Refseq: NP_003681
• MIM: 603424
• UniProt ID: O75569