Recombinant Human PRKG2 Protein, His-tagged

• Cat.No.: PRKG2-2623H
• Product Overview: Recombinant Human PRKG2 Protein (Leu453-Leu728) with a N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Leu453-Leu728
• Description: This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein binds to and inhibits the activation of several receptor tyrosine kinases. The membrane-bound protein is a regulator of intestinal secretion, bone growth and renin secretion. Alternate splicing results in multiple transcript variants encoding distinct isoforms whose regulatory N-termini differ in length but whose C-terminal catalytic domains are identical.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 61.8 kDa
  Accurate Molecular Mass: 62 kDa
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 90%
• Applications: Cell culture; Activity Assays.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: PRKG2 protein kinase, cGMP-dependent, type II [ Homo sapiens (human) ]
• Official Symbol: PRKG2
• Synonyms: PRKG2; protein kinase, cGMP-dependent, type II; cGMP-dependent protein kinase 2; cGKII; PRKGR2; cGK2; cGK 2; cGMP-dependent protein kinase II
• Gene ID: 5593
• mRNA Refseq: NM_006259
• Protein Refseq: NP_006250
• MIM: 601591
• UniProt ID: Q13237