Prkg2
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Official Full Name
protein kinase, cGMP-dependent, type II -
Synonyms
PRKG2;protein kinase, cGMP-dependent, type II;cGMP-dependent protein kinase 2;cGKII;PRKGR2;cGK2;cGK 2;cGMP-dependent protein kinase II
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Mouse
- Sf9 Cells
- Mammalian Cells
- HEK293
- Insect Cells
- E.coli
- Sf21 Cells
- GST
- His
- Non
- Flag
- Avi
- Fc
- DDK
- Myc
Involved Pathway
Prkg2 involved in several pathways and played different roles in them. We selected most pathways Prkg2 participated on our site, such as cGMP-PKG signaling pathway,Gap junction,Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with Prkg2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Platelet activation | LCP2,PRKACG,ITGB1,P2RY1,PLCB2,PIK3R5,PLCG2,ITPR3,STIM1,SRC |
| Long-term depression | CRH,GRID2,PRKCG,IGF1R,GNAI3,PLA2G4F,PLCB2,PPP2R1B,MAPK3,GNAI1 |
| cGMP-PKG signaling pathway | ATP1B3,SLC25A31,ATP1B2,CREB3L1,PIK3CG,PIK3CA,PPP3CC,CALM4,NFATC1,SLC8A1 |
| Salivary secretion | SLC9A1,LYZ1,CST4,TRPV6,AQP5,CAP18,PLCB3,KCNN4,PRB1,PRKCG |
| Regulation of lipolysis in adipocytes | PIK3R1,PRKG1,GNAI1,LOC100328615,PDE3B,PIK3CD,PIK3R3,FABP4,IRS1,AKT2 |
| Olfactory transduction | PRKACB,OR51B2,OLFR494,OR2L2,OR12D2,RGS2,OLFR186,OR2B3,CLCA1,OR10J1 |
| Renin secretion | LOC100328615,CLCA1,PLCB4,CALML5,PRKACG,GUCY1A3,ITPR1,CALM2,CLCA2,CLCA4 |
| Gap junction | GRB2A,PDGFD,GNAI2B,PRKG1,HTR2CL1,ITPR1,PRKCG,GRM5,GNA11B,PDGFRA |
| Circadian entrainment | ITPR1,RPS6KA5,CAMK2B,GNG13,GNAS,GRIN2B,MAPK3,PER1,GNG10,MTNR1B |
Protein Function
Prkg2 has several biochemical functions, for example, ATP binding,cGMP binding,cGMP-dependent protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Prkg2 itself. We selected most functions Prkg2 had, and list some proteins which have the same functions with Prkg2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein kinase activity | CAMK2G1,CLK4B,RPS6KA3,NLK1,GRK1A,TRIM28,Fert2,NPR1,PAK1,PRKAA1 |
| cGMP-dependent protein kinase activity | PRKG1A,PRKG1 |
| protein homodimerization activity | HMGCR,HELT,LDB1,S100A13,E2F8,SOD1,HRSP12,PYCARD,GAMT,ATPIF1 |
| ATP binding | GALK1,EPHB4,RAD51L1,CARNS1,SLFNL1,PRKCBA,DMC1,DYRK4,PFKFB2,DDX42 |
| cGMP binding | CNGA2,PDE10A,PDE2A,PDE5A,CNGA4,PDE6C,PRKG1A,PDE6H,PDE11A,CNGA5 |
Interacting Protein
Prkg2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Prkg2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Prkg2.
saicar;PKM;CDKL5;HSP90AB1
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