Recombinant Human PRKD2

• Cat.No.: PRKD2-30220TH
• Product Overview: Recombinant full length Protein Kinase D2 protein (Human), was expressed by baculovirus in Sf9 insect cells using a N-terminal tag, MW 130 kDa.

Specification

• Species: Human
• Tag: Non
• Description: The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Tissue specificity: Widely expressed.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.Contains 1 PH domain.Contains 2 phorbol-ester/DAG-type zinc fingers.Contains 1 protein kinase domain.
• Full Length: Full L.

Gene Information

• Gene Name: PRKD2 protein kinase D2 [ Homo sapiens ]
• Official Symbol: PRKD2
• Synonyms: PRKD2; protein kinase D2; serine/threonine-protein kinase D2; DKFZP586E0820; HSPC187; PKD2
• Gene ID: 25865
• mRNA Refseq: NM_001079880
• Protein Refseq: NP_001073349
• MIM: 607074
• Uniprot ID: Q9BZL6
• Chromosome Location: 19q13.2
• Pathway: T Cell Receptor Signaling Pathway, organism-specific biosystem
• Function: ATP binding; metal ion binding; nucleotide binding; protein kinase C activity; protein kinase activity