Recombinant Human PRKACG, GST-tagged, Active

• Cat.No.: PRKACG-396H
• Product Overview: Recombinant human full-length PKAcgamma was expressed by baculovirus inSf9 cellsusing an N-terminal GST tag. MW=65 kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Description: PKA C-gamma (PKAcγ) is a third isoform of the catalytic subunit of cAMP-dependent protein kinase. It was isolated from a human testis cDNA library and was clearly derived from a gene distinct from C-alpha and C-beta and showed tissue-specific expression. Whereas at the amino acid level C-alpha and C-beta showed 93% homology, C-gamma showed only about 80% homology to both C-alpha and C-beta.The PRKACG gene is intronless, contains remnants of a poly(A) tail, is flanked by direct repeats, and is co-linear with the PRKACA gene.
• Sequence: Full-length.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: PRKACG protein kinase, cAMP-dependent, catalytic, gamma [ Homo sapiens ]
• Synonyms: PRKACG; protein kinase, cAMP-dependent, catalytic, gamma; KAPG; PKACg; cAMP-dependent protein kinase catalytic subunit gamma; EC 2.7.11.11
• Gene ID: 5568
• mRNA Refseq: NM_002732
• Protein Refseq: NP_002723
• UniProt ID: P22612
• Chromosome Location: 9q13
• MIM: 176893
• Pathway: Apoptosis; Calcium signaling pathway; Chemokine signaling pathway; Dilated cardiomyopathy; Gap junction; GnRH signaling pathway; Hedgehog signaling pathway; Insulin signaling pathway; Melanogenesis; Long-term potentiation; Progesterone-mediated oocyte maturation; Wnt signaling pathway; Vibrio cholerae infection
• Function: ATP binding; nucleotide binding; transferase activity; cAMP-dependent protein kinase activity; protein serine/threonine kinase activity; protein kinase binding