PRKACG
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Official Full Name
protein kinase, cAMP-dependent, catalytic, gamma -
Overview
Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit. -
Synonyms
PRKACG;protein kinase, cAMP-dependent, catalytic, gamma;cAMP-dependent protein kinase catalytic subunit gamma;PKACg;KAPCG_HUMAN;KAPG;PKA C gamma;PKA C-gamma;Protein kinase cAMP dependent catalytic gamma;Serine (threonine) protein kinase;OTTHUMP00000021422;serine(threonine) protein kinase
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PRKACG-1948H | Recombinant Human PRKACG, GST-tagged | E.coli | Human | GST | 1-351aa | |
| PRKACG-30211TH | Recombinant Human PRKACG | Human | Non | Full L. |
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| PRKACG-396H | Recombinant Human PRKACG, GST-tagged, Active | Sf9 Cells | Human | GST |
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| PRKACG-2867HCL | Recombinant Human PRKACG 293 Cell Lysate | HEK293 | Human | Non |
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| PRKACG-3344HF | Active Recombinant Full Length Human PRKACG Protein, GST-tagged | Sf21 Cells | Human | GST | Full L. 1-351(end) |
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Involved Pathway
PRKACG involved in several pathways and played different roles in them. We selected most pathways PRKACG participated on our site, such as MAPK signaling pathway,Ras signaling pathway,Calcium signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRKACG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Viral carcinogenesis | SRF,HIST1H2BD,ACTN2,RANBP1,HIST1H2BC,HIST1H4A,HIST1H4E,HIST1H4K,DLG1,YWHAH |
| Apoptosis | PRKAR2A,PRKAR1B,DFFB,AKT1,GZMC,DIABLOB,BIDA,DSP,NGF,PLEC |
| Dilated cardiomyopathy | PRKACB,TNF,EMD,DAG1,ITGB7,TPM2,ADRB1,ITGA4,CACNG3,CACNA2D1 |
| Progesterone-mediated oocyte maturation | PIK3R2,PLK1,CPEB1B,HSP90AA1,ANAPC5,IGF1RA,MAPK1,SPDYB,PRKACA,PGR |
| Circadian entrainment | CALM2,AKR1C1,GNB3,PRKG1,GNGT1,ADCYAP1R1,GNB4,GNAS,NOS1AP,GRIA4 |
| Bile secretion | SLC4A4,ABCB11,SLC27A5,SLC2A1,SLCO1A5,ATP1A3,BAAT,CYP7A1,Adcy4,EPHX1 |
| Inflammatory mediator regulation of TRP channels | BDKRB1,ASIC2,MAPK8,PLCB1,CYP4A10,CAMK2G,PLCG1,CYP2J2,CAMK2D,CYP2J6 |
| Parkinsons disease | NDUFA4L2,NDUFA1,UBB,PARK2,SNCA,UBE1Y1,PPIF,SLC18A2,DRD1A,NDUFB8 |
| Vibrio cholerae infection | PLCG2,PDIA4,ATP6V0C,ATP6V0B,ATP6V1A,ATP6V1C1,ATP6V1B2,MUC2,ATP6V1B1,TJP1 |
Protein Function
PRKACG has several biochemical functions, for example, ATP binding,cAMP-dependent protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRKACG itself. We selected most functions PRKACG had, and list some proteins which have the same functions with PRKACG. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cAMP-dependent protein kinase activity | PRKAA1,PRKACB,AKAP13,PRKX,PRKACA,PRKAG1 |
| ATP binding | ASNA1,ATAD5,ACTB2,DCK,FLAD1,TAE1,PTK2,UBE2M,NEK9,MCM5 |
Interacting Protein
PRKACG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRKACG here. Most of them are supplied by our site. Hope this information will be useful for your research of PRKACG.
CETP;CDK17;PRKACA
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References
- Lee, JW; Chen, H; et al. Protein Kinase A-alpha Directly Phosphorylates FoxO1 in Vascular Endothelial Cells to Regulate Expression of Vascular Cellular Adhesion Molecule-1 mRNA. JOURNAL OF BIOLOGICAL CHEMISTRY 286:6423-6432(2011).
- Yao, L; Fan, PD; et al. Dopamine and ethanol cause translocation of epsilon PKC associated with epsilon RACK: Cross-talk between cAMP-dependent protein kinase A and protein kinase C signaling pathways. MOLECULAR PHARMACOLOGY 73:1105-1112(2008).
