Recombinant Human PRDM2 Protein, MYC/DDK-tagged

• Cat.No.: PRDM2-2911H
• Product Overview: Recombinant Human PRDM2 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 25.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PRDM2 PR domain containing 2, with ZNF domain [ Homo sapiens ]
• Official Symbol: PRDM2
• Synonyms: HUMHOXY1; KMT8; MTB-ZF; RIZ; RIZ1; RIZ2
• Gene ID: 7799
• mRNA Refseq: NM_001007257
• Protein Refseq: NP_001007258
• MIM: 601196
• UniProt ID: Q13029