Recombinant Human PPM1L protein, His-tagged

• Cat.No.: PPM1L-80H
• Product Overview: Recombinant Human PPM1L, fused with N-His tag, was expressed in E. coli.

Specification

• Description: PPM1L, or PP2CE, belongs to the PP2C group of serine/threonine phosphatases, which are distinguished from other phosphatases by their structure, absolute requirement for Mg(2+) or Mn(2+), and insensitivity to okadaic acid. PP2C sregulate stress-activated protein kinase (SAPK; see MIM 601158) signaling cascades that respond to extra cellularstimuli.
• Source: E.coli
• Species: Human
• Tag: His
• Form: 20mM Tris.Cl, 50mM NaCl, 50% Glycerol, pH8.0.
• Molecular Mass: 22.2kDa(including fusion tag)
• Protein length: 196aa(including fusion tag)
• Applications: WB, ELISA, IP, antibody production, protein array
• Storage: Store at -80centigrade and avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L [ Homo sapiens ]
• Official Symbol: PPM1L
• Synonyms: PPM1L; protein phosphatase, Mg2+/Mn2+ dependent, 1L; protein phosphatase 1 (formerly 2C) like; protein phosphatase 1L; PP2CE; PP2Cepsilon; Protein phosphatase 2C epsilon isoform; PP2C epsilon; protein phosphatase 2C isoform epsilon; PPM1-LIKE; PP2C-epsilon; MGC132545; MGC132547
• Gene ID: 151742
• mRNA Refseq: NM_139245
• Protein Refseq: NP_640338
• MIM: 611931
• UniProt ID: Q5SGD2
• Chromosome Location: 3q26.1
• Pathway: Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Sphingolipid de novo biosynthesis, organism-specific biosystem; Sphingolipid metabolism, organism-specific biosystem
• Function: hydrolase activity; metal ion binding; protein serine/threonine phosphatase activity