Recombinant Human PPIE, His-tagged

• Cat.No.: PPIE-26336TH
• Product Overview: Recombinant full length human Cyclophilin E with His tag; 337 amino acids, 37.5 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified.
• Conjugation: HIS
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20mM Tris, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequences of amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMATT KRVLYVGGLA EEVDDKVLHA AFIPFGDITD IQIPLDYETE KHRGFAFVEF ELAEDAAAAI DNMNESELFG RTIRVNLAKP MRIKEGSSRP VWSDDDWLKK FSGKTLEENK EEEGSEPPKA ETQEGEPIAK KARSNPQVYM DIKIGNKPAG RIQMLLRSDV VPMTAENFRC LCTHEKGFGF KGSSFHRIIP QFMCQGGDFT NHNGTGGKSI YGKKFDDENF ILKHTGPGLL SMANSGPNTN GSQFFLTCDK TDWLDGKHVV FGEVTEGLDV LRQIEAQGSK DGKPKQKVII ADCGEYV
• Full Length: Full L.

Gene Information

• Gene Name: PPIE peptidylprolyl isomerase E (cyclophilin E) [ Homo sapiens ]
• Official Symbol: PPIE
• Synonyms: PPIE; peptidylprolyl isomerase E (cyclophilin E); peptidyl-prolyl cis-trans isomerase E; cyclophilin 33; cyclophilin E; CyP 33; MGC3736; MGC111222; peptidyl prolyl cis trans isomerase E; peptidylprolyl isomerase E; isoform 1; PPIase E; rotamase E
• Gene ID: 10450
• mRNA Refseq: NM_001195007
• Protein Refseq: NP_001181936
• MIM: 602435
• Uniprot ID: Q9UNP9
• Chromosome Location: 1p32
• Pathway: Spliceosome, organism-specific biosystem; Spliceosome, conserved biosystem; Spliceosome, 35S U5-snRNP, organism-specific biosystem
• Function: RNA binding; RNA binding; cyclosporin A binding; isomerase activity; nucleotide binding