Recombinant Human PPIB Protein, His-tagged

• Cat.No.: PPIB-266H
• Product Overview: Recombinant Human PPIB(Tyr47~Glu216) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Tyr47~Glu216
• Description: The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 20.4kDa
• Identity: Reconstitute in PBS or others
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: PPIB peptidylprolyl isomerase B (cyclophilin B) [ Homo sapiens ]
• Official Symbol: PPIB
• Synonyms: PPIB; peptidylprolyl isomerase B (cyclophilin B); peptidyl-prolyl cis-trans isomerase B; CYPB; OI9; PPIase B; rotamase B; S-cyclophilin; cyclophilin-like protein; SCYLP; CYP-S1; MGC2224; MGC14109
• Gene ID: 5479
• mRNA Refseq: NM_000942
• Protein Refseq: NP_000933
• MIM: 123841
• UniProt ID: P23284