Recombinant Human POLH, His-tagged

• Cat.No.: POLH-1833H
• Product Overview: Recombinant Human POLH protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 1-352aa
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: POLH polymerase (DNA directed), eta [ Homo sapiens ]
• Official Symbol: POLH
• Synonyms: POLH; polymerase (DNA directed), eta; DNA polymerase eta; RAD30A; XP V; RAD30 homolog A; xeroderma pigmentosum variant type protein; XPV; XP-V; RAD30; FLJ16395; FLJ21978
• Gene ID: 5429
• mRNA Refseq: NM_006502
• Protein Refseq: NP_006493
• MIM: 603968
• UniProt ID: Q9Y253
• Chromosome Location: 6p21
• Pathway: DNA Damage Bypass, organism-specific biosystem; DNA Repair, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem; Translesion synthesis by DNA polymerases bypassing lesion on DNA template, organism-specific biosystem; Translesion synthesis by Pol eta, organism-specific biosystem
• Function: DNA-directed DNA polymerase activity; DNA-directed DNA polymerase activity; damaged DNA binding; metal ion binding; nucleotidyltransferase activity; transferase activity