Recombinant Human PNKP Protein, MYC/DDK-tagged

• Cat.No.: PNKP-2145H
• Product Overview: Recombinant human PNKP protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.[provided by RefSeq, Sep 2010].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 56.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PNKP polynucleotide kinase 3-phosphatase [ Homo sapiens ]
• Official Symbol: PNKP
• Synonyms: AOA4; EIEE10; MCSZ; PNK
• Gene ID: 11284
• mRNA Refseq: NM_007254
• Protein Refseq: NP_009185
• MIM: 605610
• UniProt ID: Q96T60