Recombinant Human PLOD3 cell lysate
Cat.No. : | PLOD3-1379HCL |
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- Gene Information
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Species : | Human |
Tag : | Non |
Description : | The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. |
Size : | 100 ul |
Storage Buffer : | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : | Western Blot; |
Gene Name | PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 [ Homo sapiens ] |
Official Symbol | PLOD3 |
Synonyms | PLOD3; procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3; procollagen-lysine,2-oxoglutarate 5-dioxygenase 3; LH3; lysyl hydroxlase 3; lysyl hydroxylase 3; lysine hydroxylase 3; |
Gene ID | 8985 |
mRNA Refseq | NM_001084 |
Protein Refseq | NP_001075 |
MIM | 603066 |
UniProt ID | O60568 |
Chromosome Location | 7q22.1 |
Pathway | Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem; Other types of O-glycan biosynthesis, organism-specific biosystem; Other types of O-glycan biosynthesis, conserved biosystem; |
Function | L-ascorbic acid binding; iron ion binding; metal ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; procollagen glucosyltransferase activity; procollagen-lysine 5-dioxygenase activity; protein binding; |
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◆ Cell & Tissue Lysates | ||
PLOD3-1379HCL | Recombinant Human PLOD3 cell lysate | +Inquiry |
Not For Human Consumption!
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