Recombinant Human PKP1 Protein, MYC/DDK-tagged

• Cat.No.: PKP1-1882H
• Product Overview: Recombinant human PKP1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 80.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PKP1 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) [ Homo sapiens ]
• Official Symbol: PKP1
• Synonyms: B6P
• Gene ID: 5317
• mRNA Refseq: NM_000299
• Protein Refseq: NP_000290
• MIM: 601975
• UniProt ID: Q13835