Recombinant Human PIP4K2B

• Cat.No.: PIP4K2B-30967TH
• Product Overview: Recombinant full length human PIP5K2 beta expressed in Baculovirus system; amino acids 1-416, 47kDa.

Specification

• Species: Human
• Tag: Non
• Protein Length: 1-416 a.a.
• Description: The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor.
• Tissue specificity: Highly expressed in brain, heart, pancreas, skeletal muscle and kidney. Detected at lower levels in placenta, lung and liver.
• Biological activity: PIP4K2B-30967TH contains no detectable protease, DNase and RNase activity.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Contains 1 PIPK domain.
• Full Length: Full L.

Gene Information

• Gene Name: PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta [ Homo sapiens ]
• Official Symbol: PIP4K2B
• Synonyms: PIP4K2B; phosphatidylinositol-5-phosphate 4-kinase, type II, beta; phosphatidylinositol 4 phosphate 5 kinase, type II, beta , PIP5K2B; phosphatidylinositol-5-phosphate 4-kinase type-2 beta; PIP5KIIB; PIP5KIIbeta
• Gene ID: 8396
• mRNA Refseq: NM_003559
• Protein Refseq: NP_003550
• MIM: 603261
• Uniprot ID: P78356
• Chromosome Location: 17q21.2
• Pathway: B Cell Receptor Signaling Pathway, organism-specific biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem; Phosphatidylinositol signaling system, organism-specific biosystem; Phosphatidylinositol signaling system, conserved biosystem
• Function: 1-phosphatidylinositol-4-phosphate 5-kinase activity; 1-phosphatidylinositol-5-phosphate 4-kinase activity; ATP binding; nucleotide binding; receptor signaling protein activity