Recombinant Human PIN1, T7-tagged
Cat.No. : | PIN1-2901H |
Product Overview : | Recombinant HumanPIN1 (1-163 aa) is expressed in E.Coli with a T7 tag at N-terminus. |
- Specification
- Gene Information
- Related Products
- Download
Species : | Human |
Source : | E.coli |
Tag : | T7 |
Protein Length : | 1-163 a.a. |
Description : | Human Pin 1 is a peptidyl-prolyl cis/trans isomerase (PPIase) that interacts with NIMA and essential for cell cycle regulation Pin1 is nuclear PPIase containing a WW protein interaction domain, and is structurally and functionally related to Ess1/Ptf1, an essential protein in budding yeast. PPIase activity is necessary for Ess1/Pin1 function in yeast. Pin1 is thus an essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Substrates of Pin1 include the mitotic regulators (Cdc25 phosphatase and NIMA, PLK I, Wee, and Myt1 kinases), several transcription factors like Catenin, c-Jun, and the tumor suppressor protein p53, and some specific proteins like the RNA Pol II, the cytoskeleton protein tau, and the G1/S protein Cyclin D1. |
MW : | 18243 Da. |
Purity : | 90%. |
Formulation : | 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3. |
Application : | MS. SDS. |
Gene ID | 5300 |
mRNA Refseq | NM_000143 |
Protein Refseq | NP_000134 |
MIM | 136850 |
UniProt ID | P07954 |
Chromosome Location | 1q42.1 |
Function | fumarate hydratase activity, fumarate hydratase activity, lyase activity |
◆ Recombinant Proteins | ||
PIN1-2901H | Recombinant Human PIN1, T7-tagged | +Inquiry |
PIN1-1682H | Recombinant Human PIN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PIN1-6747M | Recombinant Mouse PIN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PIN1-3825H | Recombinant Human PIN1, His tagged | +Inquiry |
PIN1-1722H | Recombinant Human PIN1, GST-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
PIN1-3179HCL | Recombinant Human PIN1 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Ask a Question for All PIN1 Products
Required fields are marked with *
My Review for All PIN1 Products
Required fields are marked with *
0
Inquiry Basket