Recombinant Human Phosphodiesterase 10A, GST-tagged

• Cat.No.: PDE10A-440H
• Product Overview: Recombinant Human PDE10A, full length with N-terminal GST tag expressed in aBaculovirus infected Sf9 cellexpression system. MW = 116kDa.

Specification

• Cat. No.: PDE10A-440H
• Description: Phosphodiesterase 10A is an enzyme that in humans is encoded by the PDE10A gene.
• Source: Sf9 cell.
• Purity: >60%.
• Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT.
• Stability: >6 months at –80°C.
• Full Length: Full L.

Gene Information

• Gene Name: PDE10A phosphodiesterase 10A [ Homo sapiens ]
• Synonyms: PDE10A; phosphodiesterase 10A; FLJ11894; FLJ25677; HSPDE10A; OTTHUMP00000017586; phosphodiesterase 10A1 (PDE10A1); dJ416F21.1 (phosphodiesterase 10A); EC 3.1.4.17; EC 3.1.4.35
• Gene ID: 10846
• mRNA Refseq: NM_001130690
• Protein Refseq: NP_001124162
• MIM: 610652
• UniProt ID: Q9Y233
• Chromosome Location: 6q26
• Pathway: Progesterone-mediated oocyte maturation; Purine metabolism; Signaling by GPCR
• Function: 3",5"-cyclic-GMP phosphodiesterase activity; cAMP binding; cGMP binding; hydrolase activity; magnesium ion binding; nucleotide binding; zinc ion binding