Recombinant Human PEX14 Protein, His-tagged

• Cat.No.: PEX14-2578H
• Product Overview: Recombinant Human PEX14 Protein (Thr31-Asp377) with a N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Thr31-Asp377
• Description: This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 41.8 kDa
  Accurate Molecular Mass: 60 kDa
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: PEX14 peroxisomal biogenesis factor 14 [ Homo sapiens (human) ]
• Official Symbol: PEX14
• Synonyms: PEX14; peroxisomal biogenesis factor 14; peroxisomal membrane protein PEX14; peroxin-14; PTS1 receptor docking protein; PTS1 receptor-docking protein; NF-E2 associated polypeptide 2; peroxisomal membrane anchor protein PEX14; peroxisomal membrane anchor protein Pex14p; NAPP2; Pex14p; dJ734G22.2; MGC12767
• Gene ID: 5195
• mRNA Refseq: NM_004565
• Protein Refseq: NP_004556
• MIM: 601791
• UniProt ID: O75381