Recombinant Human PEX14 cell lysate

• Cat.No.: PEX14-1336HCL

Specification

• Description: This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot
• Tag: Non

Gene Information

• Gene Name: PEX14 peroxisomal biogenesis factor 14 [ Homo sapiens ]
• Official Symbol: PEX14
• Synonyms: PEX14; peroxisomal biogenesis factor 14; peroxisomal membrane protein PEX14; peroxin-14; PTS1 receptor docking protein; PTS1 receptor-docking protein; NF-E2 associated polypeptide 2; peroxisomal membrane anchor protein PEX14; peroxisomal membrane anchor protein Pex14p; NAPP2; Pex14p; dJ734G22.2; MGC12767
• Gene ID: 5195
• mRNA Refseq: NM_004565
• Protein Refseq: NP_004556
• UniProt ID: O75381
• Chromosome Location: 1p36.22
• Pathway: Peroxisome, organism-specific biosystem; Peroxisome, conserved biosystem
• Function: protein N-terminus binding; protein binding; transcription corepressor activity