Recombinant Human PEBP1
Cat.No. : | PEBP1-29533TH |
Product Overview : | Recombinant human PEBP1 was expressed in E. coli and purified by using conventional chromatography techniques. |
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Species : | Human |
Source : | E.coli |
Tag : | Non |
Description : | Phosphatidylethanolamine binding protein 1 (PEBP1) is a member of the phosphatidylethanolamine-binding protein family and a serine protease inhibitor which inhibits thrombin, neuropsin. PEBP1 plays a pivotal modulatory role in several protein kinase signaling cascades. Protein kinase C (PKC) phosphorylates PEBP1, resulting in release of Raf-1 and activation of MEK and ERK. Expressed in many tissues, PEBP1 is implicated in the regulation of such physiological processes as membrane biosynthesis, spermatogenesis, neural development, and metastasis suppression. |
Molecular Mass : | 21 kDa (187aa), confirmed by MALDI-TOF. |
Form : | Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol |
Purity : | > 95% by SDS - PAGE |
Endotoxin Level : | < 1.0 EU per 1 microgram of protein (determined by LAL method ) |
Applications : | SDS-PAGE |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Storage : | Can be stored at +4oC short term (1-2 weeks). For long term storage, aliquot and store at -20oC or -70oC. Avoid repeated freezing and thawing cycles. |
OfficialSymbol : | PEBP1 |
Gene Name | PEBP1 phosphatidylethanolamine binding protein 1 [ Homo sapiens ] |
Synonyms | PEBP1; phosphatidylethanolamine binding protein 1; PBP, prostatic binding protein; phosphatidylethanolamine-binding protein 1; HCNP; hippocampal cholinergic neurostimulating peptide; PEBP; Raf kinase inhibitory protein; RKIP |
Gene ID | 5037 |
mRNA Refseq | NM_002567 |
Protein Refseq | NP_002558 |
MIM | 604591 |
UniProt ID | P30086 |
Chromosome Location | 12q24.23 |
Pathway | Aurora B signaling; EGFR1 Signaling Pathway; ErbB1 downstream signaling; TNF-alpha/NF-kB Signaling Pathway |
Function | ATP binding; mitogen-activated protein kinase binding; phosphatidylethanolamine binding; receptor binding; serine-type endopeptidase inhibitor activity |
◆ Recombinant Proteins | ||
PEBP1-4028R | Recombinant Rat PEBP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PEBP1-29533TH | Recombinant Human PEBP1 | +Inquiry |
PEBP1-601H | Recombinant Human PEBP1 Protein (Met1-Lys187) | +Inquiry |
PEBP1-12619M | Recombinant Mouse PEBP1 Protein | +Inquiry |
PEBP1-30791TH | Recombinant Human PEBP1 | +Inquiry |
◆ Cell & Tissue Lysates | ||
PEBP1-3311HCL | Recombinant Human PEBP1 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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