Recombinant Human PEBP1

Cat.No. : PEBP1-29533TH
Product Overview : Recombinant human PEBP1 was expressed in E. coli and purified by using conventional chromatography techniques.
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Species : Human
Source : E.coli
Tag : Non
Description : Phosphatidylethanolamine binding protein 1 (PEBP1) is a member of the phosphatidylethanolamine-binding protein family and a serine protease inhibitor which inhibits thrombin, neuropsin. PEBP1 plays a pivotal modulatory role in several protein kinase signaling cascades. Protein kinase C (PKC) phosphorylates PEBP1, resulting in release of Raf-1 and activation of MEK and ERK. Expressed in many tissues, PEBP1 is implicated in the regulation of such physiological processes as membrane biosynthesis, spermatogenesis, neural development, and metastasis suppression.
Molecular Mass : 21 kDa (187aa), confirmed by MALDI-TOF.
Form : Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol
Purity : > 95% by SDS - PAGE
Endotoxin Level : < 1.0 EU per 1 microgram of protein (determined by LAL method )
Applications : SDS-PAGE
Concentration : 1 mg/ml (determined by Bradford assay)
Storage : Can be stored at +4oC short term (1-2 weeks). For long term storage, aliquot and store at -20oC or -70oC. Avoid repeated freezing and thawing cycles.
OfficialSymbol : PEBP1
Gene Name PEBP1 phosphatidylethanolamine binding protein 1 [ Homo sapiens ]
Synonyms PEBP1; phosphatidylethanolamine binding protein 1; PBP, prostatic binding protein; phosphatidylethanolamine-binding protein 1; HCNP; hippocampal cholinergic neurostimulating peptide; PEBP; Raf kinase inhibitory protein; RKIP
Gene ID 5037
mRNA Refseq NM_002567
Protein Refseq NP_002558
MIM 604591
UniProt ID P30086
Chromosome Location 12q24.23
Pathway Aurora B signaling; EGFR1 Signaling Pathway; ErbB1 downstream signaling; TNF-alpha/NF-kB Signaling Pathway
Function ATP binding; mitogen-activated protein kinase binding; phosphatidylethanolamine binding; receptor binding; serine-type endopeptidase inhibitor activity

Not For Human Consumption!

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