Recombinant Human PDZ Domain Containing 11, His-tagged

• Cat.No.: PDZD11-7211H
• Product Overview: Recombinant human PDZD11 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 18.5 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-140aa
• Description: PDZD11, also known as AIPP1a, is a cytosolic protein which contains one PDZ (DHR) domain. This protein bears resemblance to members of the MALS / VELIS family of proteins. It contains but one PDZ domain that apparently interacts with the C-terminus of partner proteins. PDZD11 is ubiquitously expressed, and appears to target calcium and copper ATPases to basolateral cell membranes. It is a transiently interacting partner of the PMCA b-splice forms that may play a role in their sorting to or from the plasma membrane.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT.
• Molecular Mass: 18.5 kDa (163aa), confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMDSRIPY DDYPVVFLPA YENPPAWIPP HERVHHPDYN NELTQFLPRT ITLKKPPGAQ LGFNIRGGKA SQLGIFISKV IPDSDAHRAG LQEGDQVLAV NDVDFQDIEH SKAVEILKTA REISMRVRFF PYNYHRQKER TVH
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: PDZD11 PDZ domain containing 11 [ Homo sapiens ]
• Official Symbol: PDZD11
• Synonyms: PDZD11; PDZ domain containing 11; PDZK11; PDZ domain-containing protein 11; ATPase-interacting PDZ protein; PISP; AIPP1
• Gene ID: 51248
• mRNA Refseq: NM_016484
• Protein Refseq: NP_057568
• MIM: 300632
• UniProt ID: Q5EBL8
• Chromosome Location: Xq13.1
• Function: protein C-terminus binding; protein binding