Recombinant Human PDIA2 protein, His & T7-tagged

• Cat.No.: PDIA2-7047H
• Product Overview: Recombinant Human PDIA2 aa. (Leu309~Leu525 (Accession # Q13087)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Leu309~Leu525
• Description: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. The protein plays a role in the folding of nascent proteins in the endoplasmic reticulum by forming disulfide bonds through its thiol isomerase, oxidase, and reductase activity.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 27.8kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 5.3.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: PDIA2 protein disulfide isomerase family A member 2 [ Homo sapiens (human) ]
• Official Symbol: PDIA2
• Synonyms: PDIA2; protein disulfide isomerase family A member 2; PDI; PDA2; PDIP; PDIR; protein disulfide-isomerase A2; Rho GDP dissociation inhibitor gamma; pancreas-specific protein disulfide isomerase; pancreatic protein disulfide isomerase; protein disulfide isomerase, pancreatic; protein disulfide isomerase-associated 2
• Gene ID: 64714
• mRNA Refseq: NM_006849.2
• Protein Refseq: NP_006840.2
• UniProt ID: Q13087