Recombinant Human PDGFRL protein, His & GST-tagged

• Cat.No.: PDGFRL-8159H
• Product Overview: Recombinant Human PDGFRL aa. (Gln22~Ser375 (Accession# Q15198)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: Gln22~Ser375
• Description: This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 69.5kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 9.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.05% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: PDGFRL platelet derived growth factor receptor like [ Homo sapiens (human) ]
• Official Symbol: PDGFRL
• Synonyms: PDGRL; PRLTS; PDGF receptor beta-like tumor suppressor; PDGFR-like protein; platelet-derived growth factor-beta-like tumor suppressor; platelet-derived growth factor receptor-like protein
• Gene ID: 5157
• mRNA Refseq: NM_006207.2
• Protein Refseq: NP_006198.1
• UniProt ID: Q15198