Recombinant Human PDE6D, His-tagged

• Cat.No.: PDE6D-29160TH
• Product Overview: Recombinant full length Human PDE6 delta with a C-terminal 8 amino acid His tag; predicted MWt 18.4 kDa inclusive of tag

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 150 amino acids
• Description: Retinal rod rhodopsin-sensitive cGMP 3,5-cyclic phosphodiesterase subunit delta is an enzyme that in humans is encoded by the PDE6D gene.
• Conjugation: HIS
• Molecular Weight: 18.400kDa inclusive of tags
• Tissue specificity: Retina.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 10% Glycerol, 0.02% DTT, 0.58% Sodium chloride
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV GSHHHHHH
• Sequence Similarities: Belongs to the PDE6D/unc-119 family.

Gene Information

• Gene Name: PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta [ Homo sapiens ]
• Official Symbol: PDE6D
• Synonyms: PDE6D; phosphodiesterase 6D, cGMP-specific, rod, delta; retinal rod rhodopsin-sensitive cGMP 3,5-cyclic phosphodiesterase subunit delta
• Gene ID: 5147
• mRNA Refseq: NM_002601
• Protein Refseq: NP_002592
• MIM: 602676
• Uniprot ID: O43924
• Chromosome Location: 2q35-q36
• Pathway: Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem
• Function: 3,5-cyclic-nucleotide phosphodiesterase activity; GTPase inhibitor activity; protein binding