Recombinant Human PDE1B Protein, His/GST-tagged
Cat.No. : | PDE1B-042H |
Product Overview : | Recombinant N-terminal His-GST-tagged full length human PDE1B1 protein (1-536) was expressed in insect cells. |
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Species : | Human |
Source : | Insect Cells |
Tag : | GST&His |
Protein Length : | 1-536 |
Description : | The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Form : | Lyophilized |
Molecular Mass : | 89.2 kDa |
Endotoxin : | <1.0 EU/ μg, determined by the LAL endotoxin assay. |
Purity : | ≥94% estimated by SDS-PAGE |
Stability : | ≥ 1 year |
Storage : | At -80 centigrade. |
Storage Buffer : | Sterile 50 mM Tris, pH 8.0, with 100 mM sodium chloride |
Gene Name | PDE1B phosphodiesterase 1B [ Homo sapiens (human) ] |
Official Symbol | PDE1B |
Synonyms | PDE1B; phosphodiesterase 1B; PDE1B1; PDES1B; HEL-S-79p; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; 63 kDa Cam-PDE; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; calmodulin-stimulated phosphodiesterase PDE1B1; cam-PDE 1B; epididymis secretory sperm binding protein Li 79p; phosphodiesterase 1B, calmodulin-dependent; presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B; EC 3.1.4.17 |
Gene ID | 5153 |
mRNA Refseq | NM_000924 |
Protein Refseq | NP_000915 |
MIM | 171891 |
UniProt ID | Q01064 |
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PDE1B-6583M | Recombinant Mouse PDE1B Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
PDE1B-627HCL | Recombinant Human PDE1B cell lysate | +Inquiry |
Not For Human Consumption!
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