Recombinant Human PDCD4 cell lysate

• Cat.No.: PDCD4-1320HCL

Specification

• Description: This gene encodes a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is thought to play a role in apoptosis but the specific role has not yet been determined. Two transcripts encoding different isoforms have been identified.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot
• Tag: Non

Gene Information

• Gene Name: PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) [ Homo sapiens ]
• Official Symbol: PDCD4
• Synonyms: PDCD4; programmed cell death 4 (neoplastic transformation inhibitor); programmed cell death protein 4; H731; nuclear antigen H731; protein 197/15a; neoplastic transformation inhibitor protein; MGC33046; MGC33047
• Gene ID: 27250
• mRNA Refseq: NM_001199492
• Protein Refseq: NP_001186421
• MIM: 608610
• UniProt ID: Q53EL6
• Chromosome Location: 10q24
• Pathway: mTOR signaling pathway, organism-specific biosystem
• Function: RNA binding; binding; protein binding

Reviews

04/03/2021

Good solubility and stability in solution.

01/27/2021

The purity is good, and the results obtained after analysis by SDS-PAGE or Western blot are good.

01/12/2021

Short half-life and high clearance.

Q&As

Can PDCD4 be used as a target for sequencing signals?

Yes, PDCD4 is involved in the regulation of NF-κB signaling pathway and other biological processes of sequencing signals, and can be a target for sequencing signals.

How can changes in the expression and function of PDCD4 be assessed?

Immunodeficiency method, Western blot, fluorescence microscopy and other techniques can be used to evaluate the changes in the expression and function of PDCD4.

What is the role of PDCD4 in intestinal disease?

It may be involved in processes such as proliferation, apoptosis, and inflammatory response of intestinal epithelial cells, and is associated with intestinal diseases.

What is the role of PDCD4 in neurological disorders?

PDCD4 may be related to neuronal apoptosis, neuroinflammatory response, etc. in neurological diseases.

What is the relationship between PDCD4 and liver disease?

PDCD4 is involved in the regulation of hepatocyte growth, apoptosis and transformation, and may play a role in the occurrence and development of liver diseases.

How can the information from PDCD4 be used for the development of therapeutic strategies?

Through in-depth study of the signaling pathways and regulatory mechanisms of PDCD4, we can provide important clues for the development of therapeutic strategies for related diseases.