Recombinant Human PCMT1 protein, GST-tagged

• Cat.No.: PCMT1-194H
• Product Overview: Recombinant Human PCMT1(2-end) fused with GST tag at N-terminal was expressed in Insect cells.

Specification

• Description: PCMT1 is a member of the L-isoaspartyl/D-aspartyl protein methyltransferase family, which plays an important role in protein repair. Downregulation of PCMT1 leads to hyperactivation of MAPK pathway upon EGF stimulation. PCMT1 is regulated by cell-matrix interactions, and linked to various biological processes including wound healing, cell migration, and tumor metastasis.
• Source: Insect cells
• Species: Human
• Tag: GST
• Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: 51 kDa
• Protein length: 2-end
• Purity: >95%
• Applications: Methyltransferase Assay
• Stability: 1 year at -70 centigrade from the date of shipment
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1μg/μl

Gene Information

• Gene Name: PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase [ Homo sapiens ]
• Official Symbol: PCMT1
• Synonyms: PCMT1; protein-L-isoaspartate (D-aspartate) O-methyltransferase; protein-L-isoaspartate(D-aspartate) O-methyltransferase; protein-beta-aspartate methyltransferase; L-isoaspartyl protein carboxyl methyltransferase; protein L-isoaspartyl/D-aspartyl methyltr
• Gene ID: 5110
• mRNA Refseq: NM_001252049
• Protein Refseq: NP_001238978
• MIM: 176851
• UniProt ID: P22061
• Chromosome Location: 6q22.3-q24
• Function: protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; transferase activity