Name: Recombinant Human PCDHGA8 cell lysate
SKU: PCDHGA8-1305HCL

Species :	Human
Tag :	Non
Description :	This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Size :	100 ul
Storage Buffer :	1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications :	Western Blot;

Gene Name	PCDHGA8 protocadherin gamma subfamily A, 8 [ Homo sapiens ]
Official Symbol	PCDHGA8
Synonyms	PCDHGA8; protocadherin gamma subfamily A, 8; protocadherin gamma-A8; KIAA0327; PCDH GAMMA A8; PCDH-GAMMA-A8;
Gene ID	9708
mRNA Refseq	NM_014004
Protein Refseq	NP_054723
MIM	606295
UniProt ID	Q9Y5G5
Chromosome Location	5q31
Function	calcium ion binding;