Recombinant Human PAX6 Protein, His-tagged

Description :	This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.
Source :	E. coli
Species :	Human
Tag :	His
Form :	25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
Molecular Mass :	48 kDa
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration :	>50 ug/mL as determined by microplate BCA method

Gene Name	PAX6 paired box 6 [ Homo sapiens ]
Official Symbol	PAX6
Synonyms	PAX6; paired box 6; AN2, paired box gene 6 (aniridia, keratitis); paired box protein Pax-6; AN; aniridia; keratitis; D11S812E; WAGR; oculorhombin; aniridia type II protein; paired box homeotic gene-6; AN2; MGDA; MGC17209;
Gene ID	5080
mRNA Refseq	NM_001604
Protein Refseq	NP_001595
MIM	607108
UniProt ID	P26367