Recombinant Human paired related homeobox 1, His-tagged

• Cat.No.: PRRX1-285H
• Product Overview: PRRX1, 1-217aa, Human, His tag, E.coli

Specification

• Description: Paired related homeobox 1, also known as PRRX1, acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer. Recombinant human PRRX1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT
• Molecular Mass: 26.9 kDa (241aa) confirmed by MALDI-TOF(Molecular size on SDS-PAGE will appear higher)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMTSSYG HVLERQPALG GRLDSPGNLD TLQAKKNFSV SHLLDLEEAG DMVAAQADEN VGEAGRSLLE SPGLTSGSDT PQQDNDQLNS EEKKKRKQRR NRTTFNSSQL QALERVFERT HYPDAFVRED LARRVNLTEA RVQVWFQNRR AKFRRNERAM LANKNASLLK SYSGDVTAVE QPIVPRPAPR PTDYLSWGTA SPYRSSSLPR CCLHEGLHNG F
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25mg/ml (determined by Bradford assay)
• Protein length: 1-217 a.a.

Gene Information

• Gene Name: PRRX1 paired related homeobox 1 [ Homo sapiens ]
• Official Symbol: PRRX1
• Synonyms: PRRX1; paired related homeobox 1; paired mesoderm homeo box 1 , PMX1; paired mesoderm homeobox protein 1; PHOX1; PRX-1; homeobox protein PHOX1; paired mesoderm homeo box 1; paired-related homeobox protein 1; paired mesoderm homeobox 1 isoform pmx-1b; PMX1; PRX1; AGOTC
• Gene ID: 5396
• mRNA Refseq: NM_006902
• Protein Refseq: NP_008833
• MIM: 167420
• UniProt ID: P54821
• Chromosome Location: 1q24.3
• Function: sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity