Recombinant Human PADI3 cell lysate

• Cat.No.: PADI3-1274HCL

Specification

• Species: Human
• Tag: Non
• Description: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: PADI3 peptidyl arginine deiminase, type III [ Homo sapiens ]
• Official Symbol: PADI3
• Synonyms: PADI3; peptidyl arginine deiminase, type III; protein-arginine deiminase type-3; PDI3; peptidylarginine deiminase III; protein-arginine deiminase type III; PAD3; MGC126307; MGC126308
• Gene ID: 51702
• mRNA Refseq: NM_016233
• Protein Refseq: NP_057317
• MIM: 606755
• UniProt ID: Q9ULW8
• Chromosome Location: 1p36.13
• Pathway: protein citrullination, organism-specific biosystem; protein citrullination, conserved biosystem
• Function: calcium ion binding; hydrolase activity; protein-arginine deiminase activity