Recombinant Human P2RX4 Protein, His-tagged

• Cat.No.: P2RX4-2537H
• Product Overview: Recombinant Human P2RX4 Protein (Asn75-Asn338) with a N-His tag was expressed in E. coli.

Specification

• Description: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 33.2 kDa
  Accurate Molecular Mass: 33 kDa
• Protein length: Asn75-Asn338
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: P2RX4 purinergic receptor P2X, ligand-gated ion channel, 4 [ Homo sapiens (human) ]
• Official Symbol: P2RX4
• Synonyms: P2RX4; purinergic receptor P2X, ligand-gated ion channel, 4; P2X purinoceptor 4; P2X4; ATP receptor; purinoceptor P2X4; P2X receptor, subunit 4; purinergic receptor P2X4; ATP-gated cation channel protein; P2X4R
• Gene ID: 5025
• mRNA Refseq: NM_001256796
• Protein Refseq: NP_001243725
• MIM: 600846
• UniProt ID: Q99571