Recombinant Human OTC Protein, His-tagged

• Cat.No.: OTC-325H
• Product Overview: Recombinant Human OTC fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
• Form: 50mM Tris, pH8.0, 500mM NaCl, 10% glycerol.
• Molecular Mass: 36.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: OTC ornithine carbamoyltransferase [ Homo sapiens ]
• Official Symbol: OTC
• Synonyms: OTC; ornithine carbamoyltransferase; ornithine carbamoyltransferase, mitochondrial; OTCase; ornithine transcarbamylase; OCTD; MGC129967; MGC129968; MGC138856
• Gene ID: 5009
• mRNA Refseq: NM_000531
• Protein Refseq: NP_000522
• MIM: 300461
• UniProt ID: P00480