Recombinant Human OSCAR, His-tagged

Description :	Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. OSCAR is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.?
Source :	E. coli
Species :	Human
Tag :	Non
Form :	Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Molecular Mass :	31kDa (291aa)
Protein length :	19-286aa
AA Sequence :	MGSSHHHHHH SSGLVPRGSH MGSDITPSVA IIVPPASYHP KPWLGAQPAT VVTPGVNVTL RCRAPQPAWR FGLFKPGEIA PLLFRDVSSE LAEFFLEEVT PAQGGIYRCC YRRPDWGPGV WSQPSDVLEL LVTEELPRPS LVALPGPVVG PGANVSLRCA GRLRNMSFVL YREGVAAPLQ YRHSAQPWAD FTLLGARAPG TYSCYYHTPS APYVLSQRSE VLVISWEGEG PEARPASSAP GMQAPGPPPS DPGAQAPSLS SFRPRGLVLQ PLLPQTQDSW DPAPPPSDPG V
Purity :	>85% by SDS - PAGE
Applications :	SDS-PAGE
Storage :	Can be stored at 4°C short term. For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
Concentration :	0.25 mg/ml

Gene Name	OSCAR osteoclast associated, immunoglobulin-like receptor [ Homo sapiens ]
Official Symbol	OSCAR
Synonyms	OSCAR; osteoclast associated, immunoglobulin-like receptor; osteoclast-associated immunoglobulin-like receptor; PIgR-3; hOSCAR; poly-Ig receptor 3; osteoclast-associated receptor; polymeric immunoglobulin receptor 3; osteoclast associated receptor OSCAR-S1; osteoclast associated receptor OSCAR-S2; PIGR3; MGC33613;
Gene ID	126014
mRNA Refseq	NM_206818
Protein Refseq	NP_996554
MIM	606862
UniProt ID	Q8IYS5
Chromosome Location	19q13.42
Pathway	Osteoclast differentiation, organism-specific biosystem; Osteoclast differentiation, conserved biosystem;
Function	receptor activity;