Recombinant Human NYX Protein, MYC/DDK-tagged

• Cat.No.: NYX-1850H
• Product Overview: Recombinant human NYX protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB. [provided by RefSeq, Oct 2008].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 49.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: NYX nyctalopin [ Homo sapiens ]
• Official Symbol: NYX
• Synonyms: CLRP; CSNB1; CSNB1A; CSNB4; NBM1
• Gene ID: 60506
• mRNA Refseq: NM_022567
• Protein Refseq: NP_072089
• MIM: 300278
• UniProt ID: Q9GZU5