NYX

  • Official Full Name

    nyctalopin
  • Overview

    The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.
  • Synonyms

    NYX;nyctalopin;CSNB1, CSNB4;CLRP;CSNB1;CSNB4;leucine-rich repeat protein;NBM1;CSNB1A
Cat.# Product name Source (Host) Species Tag Protein Length Price
NYX-408H Recombinant Human NYX Mammalian Cell Human His
NYX-4810Z Recombinant Zebrafish NYX Mammalian Cell Zebrafish His
NYX-1850H Recombinant Human NYX Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
NYX-3710H Recombinant Human NYX Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
NYX-3710H-B Recombinant Human NYX Protein Pre-coupled Magnetic Beads HEK293 Human
Nyx-4565M Recombinant Mouse Nyx Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK

    Involved Pathway

    NYX involved in several pathways and played different roles in them. We selected most pathways NYX participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NYX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    NYX has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by NYX itself. We selected most functions NYX had, and list some proteins which have the same functions with NYX. You can find most of the proteins on our site.

    Function Related Protein
    molecular_function NXPH4,CRYGMXL1,NKX2-4,SAP130A,RNF148,SLC15A5,ATF7IP2,C2CD2L,TMEM30C,CFAP36

    Interacting Protein

    NYX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NYX here. Most of them are supplied by our site. Hope this information will be useful for your research of NYX.

    Resources

    References

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